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Ducks vs. Trojans: Week 4 Showdown of Titans
26 Sep
Summary
- Oregon faces USC in a crucial Week 4 game on Saturday, Sept. 25, 2026.
- The matchup features high-powered offenses and potentially weak defenses.
- Oregon is favored by 3.5 points with a total over/under of 61.5.

The Oregon Ducks are preparing for a pivotal Week 4 regular-season game against the USC Trojans on Saturday, September 25, 2026. This matchup is crucial for the Ducks, especially if they aim to avoid an undefeated run through the rest of their schedule. The game is scheduled for a 4:30 pm PT start at the LA Memorial Coliseum in Los Angeles, California.
Fans can tune into the highly anticipated contest on NBC, with streaming available via Peacock. The betting odds indicate Oregon as a 3.5-point favorite, with the over/under set at 61.5, suggesting an expected high-scoring affair. Both offenses are known for their scoring prowess, while their defenses have shown vulnerabilities this season. The injury report for Oregon includes several key players with designations ranging from probable to out.