49ers Star RB McCaffrey Leaves Game with Thigh Injury

The San Francisco 49ers' dominant start to the 2026 season faced a scare on October 25, 2026, when star running back Christian McCaffrey left their Week 7 game against the Atlanta Falcons with a thigh injury. McCaffrey, a key reason for the 49ers' success, was injured early in the second quarter after scoring the game's first touchdown. He was evaluated in the medical tent and is considered questionable to return.

Following McCaffrey's exit, backup running back Kaelon Black quickly demonstrated the team's depth by breaking off a 30-yard touchdown run. Despite the potential loss of their star player, the 49ers appeared to be in firm control of the game against Atlanta in the first half. The team will monitor McCaffrey's condition closely as the season progresses.