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Chargers Suffer Setback After Statement Win: Perryman Sidelined for Weeks
9 Sep
Summary
- Chargers opened season with major win over Chiefs
- Veteran LB Denzel Perryman diagnosed with high ankle sprain
- Perryman to miss 4-6 weeks, leaving defense thin

The Los Angeles Chargers opened their 2025 season with an impressive victory over Patrick Mahomes and the Kansas City Chiefs in Brazil. However, the celebration was quickly dampened by troubling news that hit the Chargers' locker room just a day later.
Veteran linebacker Denzel Perryman, who left Sunday's game early, has been diagnosed with a high ankle sprain. NFL Network's Ian Rapoport reported that Perryman will be sidelined for multiple weeks, with the typical recovery window ranging from four to six weeks.
This is a significant blow for the Chargers' defense, which had leaned heavily on Perryman's physicality and experience in the middle of the field. Perryman, who is in his second stint with the Chargers, was expected to anchor the front seven alongside stars like Joey Bosa and Khalil Mack.
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The timing of Perryman's injury is particularly troubling, as the Chargers now face a brutal stretch of games against the Las Vegas Raiders, Buffalo Bills, and Pittsburgh Steelers. Losing their defensive leader for any length of time leaves the Chargers thin against both the run and short passing game, potentially undoing the momentum from their impressive Week 1 victory.