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Purdy's Perfection vs. Brissett's Struggles
27 Sep
Summary
- 49ers QB Brock Purdy aims for a sack-free start.
- Cardinals TE Trey McBride is a consistent passing threat.
- Christian McCaffrey eyes 100 career rushing touchdowns.
On Sunday, September 27, 2026, the Arizona Cardinals will visit the San Francisco 49ers at Levi's Stadium. San Francisco enters the matchup with a 2-0 record, averaging 31 points and 380.5 yards per game. Quarterback Brock Purdy has yet to be sacked this season, contributing to the 49ers' offensive success.
Arizona's offense has struggled, averaging just 16.5 points per game. Their primary offensive weapon has been tight end Trey McBride, who has secured 17 catches for 136 yards and two touchdowns. Running back Christian McCaffrey has been a key contributor for the 49ers, recently reaching 100 career regular-season touchdowns and averaging 134.5 rushing yards per game.
Cardinals quarterback Jacoby Brissett faces a tough challenge against the 49ers' defense, which has allowed only 10 points per game and recorded four sacks already. Arizona's defense has allowed 22.5 points per game. The 49ers are favored by 8.5 points in this contest.
