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49ers Return Home, Face Struggling Dolphins
20 Sep
Summary
- 49ers host Dolphins in home opener after Australia trip.
- Dolphins struggle with new coach and QB after Week 1 loss.
- San Francisco is a heavy favorite by nearly two touchdowns.

The San Francisco 49ers are set to play their first home game of the 2026 season at Levi's Stadium in Week 2, immediately following their return from Australia. They secured a decisive 27-7 victory over the Los Angeles Rams in their international opener, though wide receiver De'Zhaun Stribling and tight end Jacob Tonges sustained significant injuries.
The Miami Dolphins enter Week 2 with considerable changes, having fired head coach Mike McDaniel and released quarterback Tua Tagovailoa during the offseason. Under new head coach Jeff Hafley, the Dolphins lost their season opener 27-13 to the Las Vegas Raiders. Quarterback Malik Willis struggled in his debut, throwing an interception and taking five sacks.
Despite minor concerns about kicker Eddie Pineiro and running back Kaelon Black, both are expected to play for the 49ers. The Dolphins will be without EDGE Chop Robinson and inside linebacker Ronnie Harrison. The 49ers are heavily favored by 13.5 points, making their performance against the Dolphins the primary narrative for the game.