Who did the 49ers activate for their game against Indianapolis?

The 49ers activated defensive end Yetur Gross-Matos and elevated linebacker Eric Kendricks and cornerback Eli Apple.

When will Eric Kendricks make his 49ers debut?

Eric Kendricks is set to make his 49ers debut in the Week 16 game against the Indianapolis Colts.

What injury kept Yetur Gross-Matos sidelined for the 49ers?

Yetur Gross-Matos was sidelined by a hamstring injury he sustained in early October.

Home / Sports / 49ers Bolster Defense Ahead of Crucial Matchup

49ers Bolster Defense Ahead of Crucial Matchup

23 Dec, 2025

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Summary

Yetur Gross-Matos returns from injured reserve after two months.
Eric Kendricks will make his 49ers debut after joining the practice squad.
Eli Apple returns for his second game with the team.

49ers Bolster Defense Ahead of Crucial Matchup

The San Francisco 49ers have activated three defensive players for their upcoming Week 16 game against the Indianapolis Colts, bolstering their defensive unit for the crucial matchup. Defensive end Yetur Gross-Matos has been cleared to play after spending time on injured reserve due to a hamstring injury sustained in early October.

Adding further depth, veteran linebacker Eric Kendricks is slated to make his 49ers debut. Kendricks joined the team's practice squad late last month and brings significant experience from his previous tenure with the Dallas Cowboys. Cornerback Eli Apple has also been elevated and will be available for the contest, having previously played in one game for San Francisco earlier this season.

These defensive reinforcements come at a critical point in the season as the 49ers prepare for their home game on Monday night. The return of Gross-Matos and the debut of Kendricks, alongside Apple's increased availability, aim to strengthen the team's defensive performance heading into the final stretch of the regular season.