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Ultrasound Offers Hope for Vision Restoration
15 May
Summary
- Ultrasound can modulate neural activities in mouse brains and amphibian retinas.
- Sonogenetics uses ultrasound to activate genetically modified neurons on demand.
- Chinese researchers successfully treated glaucoma patients with ultrasound in 2025.

Ultrasound, sound waves beyond human hearing, is demonstrating significant therapeutic potential, especially for vision restoration. Researchers have observed that low-intensity ultrasound can modulate neural activity in animal models, like mouse brains and amphibian retinas, a phenomenon that has sparked interest in sonogenetics.
Sonogenetics leverages ultrasound's non-invasive nature to precisely control genetically engineered neurons. By introducing genes for mechanosensitive proteins, neurons become responsive to ultrasound waves, allowing for targeted activation. This approach is particularly promising for conditions where the optic nerve is impaired, such as glaucoma.
Groundbreaking clinical application was seen in 2025 when researchers in China successfully treated 16 glaucoma patients using ultrasound. Additionally, a US-based foundation has developed an ultrasound device aimed at reducing intraocular pressure to treat glaucoma, pending regulatory clearance.
Beyond eye treatments, high-intensity focused ultrasound also offers therapeutic benefits, including precise cancer treatment by rapidly heating and destroying tumor cells while sparing surrounding healthy tissue.