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Breakthrough Nanoinjection Targets Breast Cancer
22 Dec
Summary
- Nanoinjection system delivers doxorubicin directly into cancer cells.
- Demonstrated 23 times lower inhibitory concentration than free doxorubicin.
- Silicon nanotube base is biocompatible and non-toxic.

An international research team, spearheaded by IIT Madras, has engineered a pioneering nanoinjection platform designed to revolutionize breast cancer therapy. This advanced system employs nanoarchaeosomes within silicon nanotubes to deliver the chemotherapy drug doxorubicin directly into malignant cells. By doing so, it significantly enhances therapeutic efficacy while drastically reducing harm to surrounding healthy tissues. Initial studies in cell cultures and chick embryos showed remarkable success in eradicating cancer cells and inhibiting tumor growth.
The new platform, dubbed NAD-SiNTs, proved to be substantially more potent than free doxorubicin, requiring much lower doses. This translates to a potential reduction in treatment expenses and a decrease in adverse side effects for patients. The inherent biocompatibility and non-toxicity of the silicon nanotube base further simplify its application and enhance its suitability for widespread clinical use.
This development could particularly benefit regions with limited access to advanced cancer treatments, offering a more affordable and effective solution. Future research will concentrate on in vivo studies and regulatory approvals, paving the way for clinical trials and potential adaptation for other cancer types.




