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Brain Aging: Memory Loss Linked to Widespread Brain Changes
15 Jan
Summary
- Memory decline accelerates with increasing brain tissue shrinkage over time.
- Widespread structural brain changes, not a single region, drive memory loss.
- The link between brain atrophy and memory loss strengthens in later life.
A massive international brain study has uncovered that memory decline with age is not due to a single gene or brain region. Instead, widespread structural changes accumulating over time across the brain are responsible.
The analysis, involving over 10,000 MRI scans and 13,000 memory tests from nearly 4,000 healthy adults, found that memory loss accelerates as brain tissue shrinkage increases, especially in later life.
This research suggests that memory aging reflects large-scale, network-level structural changes, indicating a distributed vulnerability across the brain rather than damage in one isolated area.
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