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Gut Bacteria Predict Melanoma Recurrence
18 Apr
Summary
- Gut bacteria amounts accurately predict melanoma recurrence risk.
- Regional differences exist in bacterial markers for recurrence.
- Microbiome analysis could guide future melanoma treatment.

Scientists have discovered that the types and amounts of certain bacteria in the gut can predict the likelihood of melanoma recurrence after surgery and immunotherapy. The research, involving 674 melanoma patients from a global clinical trial, found that specific gut bacterial groups accurately signaled recurrence risk in up to 94 percent of cases.
These identified bacterial markers interact with immune cells and can alter a patient's response to treatments like nivolumab and ipilimumab. This discovery offers a potential way to tailor treatments for melanoma patients by analyzing their unique gut microbiome before therapy begins.