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Weight-Loss Drugs: Muscle Loss Risk Revealed
6 Dec
Summary
- Weight-loss jabs may cause muscle loss equivalent to a decade of aging.
- Studies show 20-50% of weight lost can be lean body mass.
- Strength training is crucial to preserve muscle mass on these drugs.

A comprehensive global review, spearheaded by Canadian researchers, has uncovered a significant concern regarding the use of weight-loss medications, often referred to as 'jabs'. The study indicates that individuals taking these drugs may risk losing substantial amounts of lean muscle mass, a consequence comparable to a decade of natural aging. This loss can be substantial, with some studies reporting that 20 to 50 percent of the weight shed is lean body mass.
This decline in muscle mass is particularly worrying for older adults, as muscle naturally diminishes with age. The added effect of weight-loss drugs can exacerbate this, potentially leading to increased frailty and a higher risk of falls. Experts emphasize the growing body of evidence supporting the vital role of strength training in preserving lean muscle and bone mass during and after medication use.
While specific resistance training protocols for those on weight-loss jabs are still under investigation, current recommendations suggest individuals engage in strength exercises two to three times weekly, alongside at least 150 minutes of moderate to vigorous physical activity. Health authorities like the National Institute for Health and Care Excellence (Nice) also advise that patients prescribed these medications receive guidance on diet, nutrition, and physical activity, including strength training.



