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New Mpox Strain, More Virulent, Confirmed in US
14 May
Summary
- A more virulent strain of mpox, clade I, has been confirmed in the US.
- The case was detected in a person who recently traveled to Western Europe.
- Health officials are also monitoring rare hantavirus cases in Europe.

A more virulent strain of mpox, known as clade I, has been confirmed for the first time in the United States. The case was identified in Connecticut in an individual who had recently traveled to Western Europe. This clade is historically associated with more severe illness and higher mortality rates compared to clade II, which was responsible for the 2022 global outbreak.
While the Connecticut Department of Public Health has stated that this specific mpox case does not present a risk to the broader public, they are recommending the JYNNEOS vaccine for those who may be at risk. Mpox symptoms can include fever, swollen lymph nodes, and a rash. This situation unfolds as global health entities, including the World Health Organization, also report new hantavirus cases in Spain and France. Hantavirus, though rare, can cause severe respiratory complications and is typically transmitted through contact with infected rodents.