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Single Mom Battles Rare Jaw Cancer, Fights for Life
17 Nov
Summary
- 39-year-old single mom diagnosed with rare, aggressive B-cell lymphoma
- Given just 14-20% chance of 5-year survival, undergoes clinical trial treatment
- Raises funds on GoFundMe to cover costs while away from her two sons

In November 2024, 39-year-old Nancy Major from Fannett, Texas, was diagnosed with a rare and aggressive form of B-cell lymphoma in her jaw. What started as a seemingly minor dental issue quickly escalated into a life-threatening battle for the single mother of two.
Major first noticed a lump in her lower jaw in January 2024 and assumed it was just an abscess. However, the lump continued to grow, accompanied by weight loss, shortness of breath, and loose teeth. Despite multiple visits to the doctor and several CT scans, the true nature of the mass was not identified until a nurse finally ordered an urgent biopsy.
The devastating diagnosis revealed that Major had a rare and extremely aggressive form of B-cell lymphoma, a type of cancer that originates in the white blood cells. Doctors warned her that she had just a 14 to 20 percent chance of living for five more years.
Fortunately, Major's cancer was caught early, and she was accepted into a lifesaving clinical trial at the National Institutes of Health in Maryland. After undergoing several rounds of intensive chemotherapy, the tumor in her jaw began shrinking rapidly, and her chances of remission have significantly improved.
However, the treatment has come at a heavy personal cost. Major has been separated from her two young sons, D'siah and Kannon, for months as she receives care far from their home in Texas. To help cover the expenses, she has turned to social media, sharing her journey on TikTok and setting up a GoFundMe campaign that has raised over $15,000 so far.
Despite the immense challenges, Major remains determined and hopeful. She has donated her hair to make wigs for other cancer patients and is driven by the belief that her "calling is bigger than [she] can see right now." With the support of her online community, this single mother is fighting to overcome the odds and return home to her beloved sons.
