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Statin Muscle Pain: What You Need to Know
5 Feb
Summary
- Muscle pain affects 10-30% of statin users, often mild.
- Statin muscle pain feels symmetrical, like workout soreness.
- Consult doctors before stopping statins; alternatives exist.

High cholesterol levels contribute to serious health issues, including heart disease and stroke. Statins are frequently prescribed alongside lifestyle changes to manage cholesterol by inhibiting a key liver enzyme involved in its production.
While effective, statins can lead to unwanted side effects, with muscle pain being the most common reason for patients to stop treatment. Real-world studies indicate that 10% to 30% of statin users experience some form of muscle discomfort, though it is often mild and manageable.
This pain is typically described as symmetrical aches, stiffness, or weakness in the limbs and shoulders, resembling post-workout soreness. It can persist even at rest. Rare but serious signs include severe weakness, dark urine, or fever. Doctors may adjust dosage, switch medications, or temporarily halt therapy to assess and manage these symptoms.




