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Soybean Oil Linked to Obesity in New Study
30 Nov
Summary
- Soybean oil's linoleic acid may promote obesity via oxylipins.
- Genetically altered mice gained less weight on soybean oil.
- Processing of fatty acids, not just calories, matters.

A recent study published in the Journal of Lipid Research indicates that soybean oil, a prevalent cooking oil in the United States, might directly contribute to obesity. The research points to the body's metabolic processing of linoleic acid, a primary component of soybean oil, as a key factor.
Scientists discovered that linoleic acid is converted into molecules known as oxylipins. Elevated levels of these oxylipins were associated with weight gain in mice. When researchers used genetically engineered mice with altered metabolic pathways that reduced oxylipin production, these mice gained significantly less weight when fed a soybean oil-rich diet compared to normal mice.
These findings suggest that the biochemical pathways through which the body metabolizes soybean oil's fatty acids could play a more significant role in fat accumulation than previously understood. While the study was conducted in mice, it raises important questions about the role of linoleic-acid-rich oils in human obesity beyond simple caloric intake.




