Rapid Cancer Test Saves Kids Weeks of Waiting

Children with suspected cancer may soon be spared unnecessary medical interventions thanks to a rapid genetic test that identifies tumour changes within days. Currently, whole genome sequencing (WGS) on the NHS takes four to six weeks, a delay that can be critical for young patients. Researchers found that quicker analysis led to improved treatment outcomes. Some children avoided invasive surgery, while others were diagnosed with benign conditions that resolved on their own.

A nationwide trial is now underway to assess if these benefits can be replicated across the wider NHS. The WGS technique compares a tumour sample with skin or saliva samples to pinpoint cellular differences, enabling precise diagnosis and targeted treatments. The study, involving 54 children, showed significant improvements in treatment for about half the patients, with two children avoiding invasive procedures for benign tumours.

Dr. Aditi Vedi, a paediatric oncologist involved in the study, highlighted the critical difference faster results make, stating, "We can return that same data just as accurate within two to three days, which means that we can actually make a meaningful difference to these patients." The national trial will involve 200 children over two years, aiming to demonstrate the test's accuracy, feasibility, and health economic benefits. If successful, NHS England aims to commission this rapid sequencing for children nationwide, eliminating postcode lotteries and ensuring broader access to this life-changing technology.