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Antidepressants in Pregnancy: Risks of Stopping Revealed
12 Feb
Summary
- Stopping antidepressants nearly doubles mental health emergency risk for pregnant women.
- Most women stopped medication, leading to over 500 more emergency visits.
- Untreated depression poses significant risks to mother and baby.

New research presented at a conference suggests that pregnant women who discontinue their antidepressants face nearly double the risk of a mental health emergency. The study, using insurance and pharmacy data from over 1,400 women in Pennsylvania, revealed that most pregnant individuals stopped their medication.
These women experienced over 500 more emergency department visits for behavioral health issues compared to those who continued treatment. Experts emphasize that while medication risks in pregnancy are often discussed, the dangers of stopping necessary treatment are equally significant.
Untreated depression during pregnancy can lead to severe consequences for both mothers and newborns, including preterm birth and increased risk of neonatal intensive care admission. For mothers, it can elevate the risk of pre-eclampsia and, in severe cases, contribute to maternal suicide.
While concerns exist regarding S.S.R.I. use and potential risks to the baby, such as persistent pulmonary hypertension or neonatal adaptation issues, robust data indicates that the benefits of treating depression often outweigh these risks. Some studies have suggested links to autism or miscarriage, but further research controlling for maternal mental illness has largely debunked these associations.
Alternative treatments like talk therapy, adequate sleep, nutrition, and exercise can also aid in managing mood disorders during pregnancy. However, experts advise that if a patient is stable on medication, it's often best not to interfere.




