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Pregabalin: The Silent Epidemic of Dependence
4 Dec
Summary
- Hundreds of thousands in the UK rely on pregabalin daily.
- Prescriptions increased 25% since 2019; deaths linked to it rose significantly.
- Experts warn pregabalin dependency is poorly understood and hard to overcome.

Pregabalin, a medication prescribed to 800,000 individuals daily in the UK for pain and anxiety, is now raising serious concerns among experts due to its dependency-forming potential. Prescriptions have seen a 25% increase since 2019, accompanied by a significant rise in associated deaths. Despite being marketed as a 'safer' alternative to drugs like opioids and benzodiazepines, some experts liken it to 'Valium on steroids'.
Patients report harrowing experiences with severe withdrawal symptoms, with some undergoing multi-year tapering processes to reduce their dosage. These withdrawal effects can be debilitating, lasting for extended periods and significantly impacting daily life, leading to job loss and relationship strain. The difficulty in discontinuing the drug, even at very low doses, is attributed to its complex action on brain receptors.
There is a growing call for greater awareness and understanding within the medical profession regarding pregabalin dependency. Experts advocate for more thorough pre-prescription discussions about potential withdrawal and urge improved patient support systems for discontinuation. The current medical approach often conflates physical dependence with addiction, contributing to stigma and inadequate patient care.




