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'Forever Chemicals' May Age Middle-Aged Men Faster
26 Feb
Summary
- PFAS chemicals may accelerate biological aging in men aged 50-65.
- Study found stronger associations in men than women.
- PFAS are linked to various health issues and are widely present.
New research indicates that per- and polyfluoroalkyl substances (PFAS), often called 'forever chemicals,' may be associated with accelerated biological aging, particularly in men aged 50 to 65. The study observed the strongest links between PFAS exposure and epigenetic aging in this specific group, with less significant associations in younger men, men over 65, and women.
These chemicals are widely present, estimated in 98% of Americans' blood. PFAS have been linked to numerous health problems, including cancer, fertility issues, and hormone disruption, due to their persistence in the environment and body. Earlier studies suggest women may eliminate certain PFAS faster than men.
The research utilized public data from 326 adults, analyzing blood samples for PFAS and measuring DNA methylation, an epigenetic marker. This data was then fed into 'biological clocks' to estimate aging. While the findings suggest a sex-specific effect, experts caution that the results indicate associations, not direct causation.
Public health recommendations include reducing exposure where feasible, such as using certified water filters and minimizing contact with stain-resistant materials. However, significant risk reduction is seen as dependent on regulatory action and environmental cleanup efforts.
