Who should avoid paracetamol according to the NHS?

Individuals with a history of allergic reactions to medicines or those with kidney or liver problems should consult a doctor before taking paracetamol.

Can I take paracetamol with other painkillers like ibuprofen?

Yes, it is safe to take paracetamol with other painkillers that do not contain paracetamol, such as ibuprofen or codeine.

What risks are associated with prolonged paracetamol use in the elderly?

Prolonged paracetamol use in the elderly may increase the risk of heart failure, gastrointestinal issues, and kidney problems.

Home / Health / Paracetamol's Hidden Risks: Study Reveals Dangers

Paracetamol's Hidden Risks: Study Reveals Dangers

30 Nov, 2025

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Summary

Prolonged paracetamol use linked to heart, kidney, and GI issues in elderly.
Study urges reconsideration of paracetamol as a first-line painkiller.
Elderly patients taking paracetamol showed increased risk of serious complications.

Paracetamol's Hidden Risks: Study Reveals Dangers

A study by the University of Nottingham has raised concerns about the prolonged use of paracetamol, particularly among elderly individuals. Research published last November analyzed medical records of individuals aged 65 and over, comparing those who used paracetamol with a control group.

The findings revealed that sustained paracetamol usage could substantially elevate the chances of serious health complications. These include an increased risk of heart failure, elevated blood pressure, gastric ulcers, and chronic kidney disease. The minimal pain-relief effect also warrants caution.

Experts suggest that paracetamol should be carefully reconsidered as a first-line treatment for long-term pain management in older adults. The research team emphasizes the need for further studies to confirm these findings and advises careful consideration of prescribing practices.