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Rethink Paracetamol for Chronic Pain, Say Experts
14 Feb
Summary
- Long-term paracetamol use may increase risks of heart issues.
- Older adults taking paracetamol face higher risk of complications.
- Experts suggest reconsidering paracetamol for chronic pain.

Paracetamol, a widely used over-the-counter painkiller, is recommended for caution in certain individuals. Those with a history of allergic reactions, kidney, or liver conditions should consult a healthcare professional before use. Additionally, individuals on blood thinners like warfarin, or medications for epilepsy or tuberculosis, must seek medical advice.
A November 2024 study from the University of Nottingham highlighted potential risks associated with prolonged paracetamol use in individuals aged 65 and above. Analysis of medical records indicated that long-term paracetamol consumption could significantly increase the risk of serious complications, including heart failure, high blood pressure, stomach ulcers, and chronic kidney disease.
These findings have prompted researchers to suggest a "careful reconsideration" of paracetamol as a primary treatment for long-term pain management. The study's lead author noted that given its minimal pain-relief effect for chronic conditions like osteoarthritis, its first-line use in older people warrants significant consideration.




