Painkiller & Antibiotic Overuse Fuels Kidney Disease Risk

The Central Drugs Standard Control Organisation (CDSCO) has alerted the public and healthcare professionals about the severe risks associated with the repeated or prolonged use of painkillers and antibiotics. This overuse is a significant contributor to chronic kidney disease and general renal impairment. Medications such as non-steroidal anti-inflammatory drugs (NSAIDs) and antibiotics are regulated under the Drugs and Cosmetics Act, 1940, and Drugs Rules, 1945, mandating their sale only via prescription.

The CDSCO's directive, issued on September 21, 2026, targets stakeholders including doctors, pharmacists, retailers, and hospitals. It stresses that these medicines must be used strictly for clinical indications, at appropriate doses, and for the correct duration. Self-medication with antibiotics, especially for viral infections, is strongly discouraged. Patients are urged to inform healthcare providers about pre-existing kidney conditions before NSAID use and to seek medical advice for persistent symptoms rather than self-treating.

Healthcare professionals are advised to consider patient factors like age and comorbidities when prescribing these drugs. The lowest effective dose for the shortest possible duration is recommended for NSAIDs, particularly for high-risk individuals. For antibiotics, doctors should adhere to antimicrobial stewardship principles, avoiding unnecessary combinations or prolonged treatments. Pharmacists and retailers must comply with regulations, and hospitals are encouraged to strengthen systems for rational prescribing and patient counseling. Awareness campaigns are also planned across states and union territories.