Home / Health / Doctor Warns of Nutrient Deficiencies from Long-Term Omeprazole Use
Doctor Warns of Nutrient Deficiencies from Long-Term Omeprazole Use
13 Nov
Summary
- Omeprazole can lower levels of essential vitamins and minerals
- Long-term use may increase risk of infections, bone fractures, and kidney problems
- Patients advised to monitor vitamin levels and speak to their doctor

According to Dr. Amir Khan, an NHS GP and resident doctor at ITV, long-term use of the common medication omeprazole can pose significant health risks. Omeprazole, a proton pump inhibitor (PPI) typically prescribed for acid reflux, heartburn, and stomach ulcers, can lower the body's absorption of essential vitamins and minerals if taken for an extended period.
Dr. Khan cautions that prolonged omeprazole use may lead to deficiencies in vitamin B12, magnesium, and calcium. This can leave patients feeling tired and increase their risk of weaker bones and other complications. Additionally, the reduction in stomach acid from omeprazole may heighten the chances of contracting infections like Clostridioides difficile (C. diff), as well as raise the risk of pneumonia and bone fractures.
To address these concerns, Dr. Khan advises patients on long-term omeprazole to have their vitamin levels checked regularly. He suggests incorporating more green leafy vegetables, nuts, and dairy into their diet to help maintain proper nutrient levels. Patients may also be able to reduce their dosage or use omeprazole intermittently, but should always consult their GP before making any changes to their medication.




