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New Drug Promises End to Jet Lag Woes
5 Feb
Summary
- A new drug, Mic-628, has been developed to reset the body clock.
- Tests showed the drug significantly shortens the time needed to adjust.
- This discovery could offer a more effective solution than current methods.

Scientists at Kanazawa University in Japan have engineered a novel compound, designated Mic-628, designed to advance the body's internal clock. This drug targets a specific clock gene, Per1, which plays a vital role in maintaining the natural sleep-wake cycle.
Experiments conducted on mice revealed that a solitary oral administration of Mic-628 accelerated the readjustment of their internal clocks from seven days down to just four. This finding suggests that Mic-628 could serve as a pioneering 'smart drug' for individuals experiencing disruptions from jet lag or shift work.
The research team posits that this new compound might offer superior efficacy compared to current methods such as light therapy or melatonin. Further studies are planned to assess its safety and effectiveness in both animal and human trials.
This development follows other recent studies that have explored dietary strategies for combating jet lag. One such study suggested that a substantial breakfast paired with skipping dinner could help reset the body clock faster for eastbound travelers.




