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Naltrexone: New Hope for Cutting Alcohol Cravings?
7 Jan
Summary
- Naltrexone, a decades-old drug, aids in reducing alcohol cravings and pleasure.
- The medication works by blocking opioid receptors in the brain's reward center.
- Common side effects include nausea, headache, and sleep disturbances.

Naltrexone, a medication first approved by the FDA in 1984 for opioid dependence and later in 1994 for alcohol use disorder, is gaining attention for its effectiveness in curbing alcohol cravings. Available as a pill or a monthly injectable therapy, it functions by blocking opioid receptors in the brain, thereby diminishing the rewarding sensations associated with alcohol consumption. This mechanism is particularly beneficial for individuals who struggle with excessive drinking or strong cravings, as highlighted by experts.
Clinical directors emphasize that naltrexone targets the brain's reward center, helping to reduce the desire for alcohol and its reinforcing effects. This makes it a valuable aid for those looking to decrease their alcohol intake. However, health professionals caution that it is not a solution for moderation for those with severe dependence. Common side effects reported include nausea, headaches, and dizziness, though these often subside as the body adjusts.
With excessive alcohol use linked to approximately 178,000 deaths annually in the United States, naltrexone offers a pharmacologically supported approach to reducing drinking behaviors. It is most effective when combined with counseling or other forms of therapy. Patients are strongly advised to obtain the medication only through a prescription from a licensed healthcare provider to ensure safety and efficacy, and to avoid counterfeit online sources.




