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MS Trial: Cancer Therapy Offers New Hope
3 Aug
Summary
- A pioneering immunotherapy treatment for cancer is being tested on MS patients.
- Numan Unees is the first patient in Sheffield to receive this experimental therapy.
- The treatment aims to reset the immune system to stop nerve damage in MS.

A pioneering clinical trial is exploring the potential of cancer immunotherapy to treat multiple sclerosis (MS). Numan Unees, diagnosed with MS six years ago and experiencing mobility loss, is the first patient in Sheffield to undergo this experimental treatment. Originally developed for certain cancers, the therapy, known as CAR T cell therapy, works by modifying a patient's immune cells to target and destroy the specific cells causing nerve damage in MS.
The Royal Hallamshire Hospital in Sheffield is one of four UK centers participating in this global trial. Researchers aim to reset the patient's immune system with a one-off treatment, potentially halting disability progression. While still in early stages, experts are optimistic, with the MS Society calling it a potential 'gamechanger' if trial results prove successful. Numan expressed hope that the treatment will allow him to regain mobility and 'start a new life'.