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Mounjaro Deaths Surge 300% in One Year
3 Feb
Summary
- Adverse reactions to Mounjaro saw a 300% increase in 2025.
- 71 deaths were recorded in the UK linked to the drug in 2025.
- Gastrointestinal issues were the most common reported reaction.

In 2025, the UK experienced a dramatic surge in adverse reactions associated with Mounjaro, with reports indicating a 300% increase and 71 deaths. Data from the MHRA's Yellow Card Scheme revealed 40,245 reactions, including 6,755 classified as serious. This represents a substantial jump from 2024, which saw 9,153 reactions and 13 fatalities.
Gastrointestinal disorders were the most commonly reported adverse effects in 2025, accounting for 37,546 reports, 19 of which were fatal. Patients like Karen Coe shared harrowing experiences, describing intense pain and severe symptoms after just one injection.
The manufacturer, Eli Lilly and Company, stated that patient safety is a top priority and that they actively monitor all safety information. Regulatory agencies assess the benefits and risks of new medicines, and patients are encouraged to report any side effects. Recent updates to product information for Mounjaro, Ozempic, and Wegovy now include a warning about a small risk of severe acute pancreatitis.




