Home / Health / Mother's Resilience Ends After Cancer Battle
Mother's Resilience Ends After Cancer Battle
23 Jan
Summary
- Lori Coble, known for resilience after losing three children, has died.
- She passed away following a battle with aggressive brain and breast cancer.
- Her family's tragedy in 2007 led to renewed calls for highway safety reform.

Lori Coble, an Orange County mother renowned for her strength following a devastating freeway crash that claimed three of her children, has died. Her passing occurred after a fight with aggressive brain and breast cancer. She was 48.
In 2007, Coble and her husband, Chris, lost their children Kyle, Emma, and Katie in a tragic accident on Interstate 5 in Southern California. Their subsequent journey through grief and their experience with IVF, leading to the birth of three more children – Ellie, Ashley, and Jake – resonated with many.
The family's profound loss became a catalyst for advocacy, reigniting demands for improved highway safety. This included efforts by the late Senator Dianne Feinstein to implement stricter trucking industry regulations.
More recently, Coble faced a new health battle, diagnosed in July with aggressive cancers. After numerous hospitalizations, she opted for hospice care earlier this month. Chris Coble announced her death on Wednesday evening, prompting widespread tributes.




