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Poor Kidneys Double Dementia Risk for Some
5 Dec
Summary
- Kidney disease nearly doubles dementia risk in vulnerable individuals.
- Poor kidney function accelerates dementia in those with brain biomarkers.
- Doctors should consider kidney health when interpreting Alzheimer's biomarkers.

A recent study has uncovered a concerning connection between kidney health and dementia risk. Researchers found that individuals with impaired kidney function who also show early biological markers for neurodegeneration face a significantly higher likelihood of developing dementia. Specifically, for those with elevated proteins linked to Alzheimer's in their blood, poor kidney health nearly doubles their risk, acting as a potent accelerator of the disease process.
The findings emphasize that kidney function plays a crucial role in modulating dementia risk, even in the absence of strong genetic predispositions. When kidneys fail, toxins and inflammatory substances accumulate in the blood, potentially damaging brain cells. Scientists suggest this toxic environment may spur on dementia in vulnerable individuals, necessitating a holistic approach to patient assessment.
These discoveries, published in the journal Neurology, underscore the importance of considering kidney health when interpreting blood-based biomarkers for Alzheimer's disease. Monitoring kidney function may help clinicians better identify individuals at risk for faster dementia progression, leading to more targeted interventions and improved patient care strategies.




