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Home / Health / Keto Diet's Cancerous Secret: Liver Risk Revealed

Keto Diet's Cancerous Secret: Liver Risk Revealed

2 Jan

•

Summary

  • High-fat, low-carb keto diets may increase liver cancer risk over two decades.
  • Liver cells adapt to high fat by becoming primitive, increasing disease vulnerability.
  • Study found nearly all mice on high-fat diets developed liver cancer within a year.
Keto Diet's Cancerous Secret: Liver Risk Revealed

Concerning new research indicates that a high-fat, low-carb ketogenic diet, often adopted for rapid weight loss, may elevate the risk of liver cancer within approximately twenty years. Scientists have discovered that persistent exposure to excessive dietary fat fundamentally alters liver cells, prompting them to shift into a more primitive state. While this adaptation helps cells survive stressful conditions, it simultaneously renders them more vulnerable to developing cancer.

The study, involving mice fed a high-fat diet, revealed that liver cells activated survival genes while shutting down those crucial for normal function. This trade-off prioritizes individual cell survival over tissue health. Within a year, nearly all the mice on this diet developed liver cancer, a process observed to unfold over about twenty years in humans, though lifestyle factors can influence this timeframe.

Researchers found that people with liver disease also exhibit this shift, with genes for cell survival increasing and normal liver function genes declining. This cellular adaptation means that if a damaging mutation occurs, cancerous development is more likely and proceeds faster. The team is now exploring whether dietary changes or weight loss drugs can reverse these cellular alterations and reduce cancer risk.

Disclaimer: This story has been auto-aggregated and auto-summarised by a computer program. This story has not been edited or created by the Feedzop team.
Research suggests that prolonged adherence to a high-fat keto diet may increase the risk of developing liver cancer over two decades.
High-fat diets can cause liver cells to adopt a more primitive state, prioritizing survival but increasing vulnerability to cancer.
While mice developed liver cancer within a year on high-fat diets, the process is estimated to take around 20 years in humans.

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