When was HIV first discovered by Françoise Barré-Sinoussi and Luc Montagnier?

HIV was first isolated by Françoise Barré-Sinoussi and Luc Montagnier in a landmark paper published on May 20, 1983.

What makes HIV so difficult to cure compared to other viruses?

HIV integrates its genetic material into host DNA and can enter a dormant state, making it invisible to the immune system and difficult to eradicate.

Is there a vaccine for HIV available today?

No, despite decades of research and investment, there is still no effective vaccine available for HIV.

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HIV: The Emperor Virus That Still Resists Cure

1 Dec

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Summary

HIV integrates into host DNA, becoming virtually indistinguishable from human cells.
The virus can enter a dormant state, hiding from the immune system.
Despite decades of research, no effective vaccine or cure exists for HIV.

HIV: The Emperor Virus That Still Resists Cure

Discovered in 1983, the human immunodeficiency virus (HIV) has presented an unprecedented challenge to medical science. Its unique ability to convert its RNA into DNA and integrate this genetic material into the host's genome makes it a permanent part of infected individuals. This integration, coupled with its capacity to enter dormant states of viral latency, allows HIV to evade immune detection and therapeutic interventions.

Despite extensive global efforts and investment, a vaccine for HIV has yet to be developed, and a cure remains largely out of reach. Antiretroviral therapies are effective at preventing viral replication and transmission, transforming HIV from a death sentence into a manageable chronic condition. However, these treatments do not clear the latent viral reservoirs, necessitating lifelong adherence and posing risks of drug resistance and side effects.