Gout Drug Colchicine Could Slash Heart Attack and Stroke Risk

According to a study published on November 13, 2025, the gout medication colchicine may offer protective benefits for people at risk of heart attack and stroke. Researchers examined the effects of low-dose colchicine in nearly 23,000 people with a history of heart disease, heart attack, or stroke. The studies found that those taking colchicine for at least six months were less likely to experience a heart attack or stroke compared to those not taking the drug.

The findings suggest that for every 1,000 people treated with low-dose colchicine, there would be nine fewer heart attacks and eight fewer strokes. Cardiovascular disease is often driven by chronic low-grade inflammation, which colchicine's anti-inflammatory properties may help address. Experts say these reductions could make a significant difference for patients living with ongoing cardiovascular risk.

While the research did not find an impact on overall mortality rates, the researchers believe colchicine presents a promising, inexpensive, and accessible option for preventing heart events in high-risk patients. Further studies are still needed to determine the drug's effects on quality of life and hospital stays. Nevertheless, this repurposed gout medication could offer a new tool in the fight against the leading cause of death globally.