What are the side effects of GLP-1 drugs according to recent reports?

Recent reports indicate that users of GLP-1 drugs are experiencing side effects such as muscle loss and weakness.

How many adults in the US are taking GLP-1 weight loss drugs?

According to a KFF poll, one in eight adults in the U.S. is currently taking a GLP-1 weight loss drug.

Are GLP-1 drugs causing muscle weakness in patients?

Some patients taking GLP-1 drugs are reporting muscle weakness as an unexpected side effect.

Home / Health / Beyond the Scale: GLP-1 Users Report Muscle Weakness

Beyond the Scale: GLP-1 Users Report Muscle Weakness

6 Dec, 2025

•

Summary

One in eight US adults now uses GLP-1 drugs for weight loss.
Patients report unexpected side effects like muscle loss.
Muscle weakness is a growing concern among drug users.

Beyond the Scale: GLP-1 Users Report Muscle Weakness

A recent poll indicates that one in eight adults across the United States is currently undergoing treatment with GLP-1 weight loss drugs. This widespread adoption has brought to light a range of unexpected side effects experienced by patients. Users are increasingly sharing their experiences, with a particular focus on muscle loss and general weakness.

These reported side effects are raising questions about the comprehensive impact of GLP-1 medications. While effective for shedding pounds, the detrimental effects on muscle mass and strength are becoming a significant talking point among those using the drugs. This emerging trend warrants further investigation into the drug's overall physiological effects.

As more individuals turn to these popular drugs for weight management, the anecdotal evidence of muscle-related issues continues to grow. Healthcare professionals and patients alike are engaging in conversations to better understand and address these unintended consequences, balancing the benefits of weight loss against potential health concerns.