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Fat Jabs Rewire Brains, Silencing Food Cravings
13 Jan
Summary
- Weight-loss jabs mimic hormones, reducing appetite and stomach emptying.
- GLP-1 agonists like Mounjaro may slow brain waves triggering food noise.
- This brain wave effect could offer new treatments for pain and addiction.
Weight-loss injections, which mimic the hormone GLP-1, are aiding millions in their weight management journey. Beyond regulating appetite and digestion, new research suggests these drugs, such as tirzepatide (Mounjaro), may influence brain activity. Scientists have found these agents can slow specific brain waves, delta-theta oscillations, which are linked to the "food noise" driving overeating.
A recent study at the University of Pennsylvania examined this effect in three patients with severe food noise. One participant taking Mounjaro showed no significant increase in these overactive brain waves, unlike the other two. This indicates a potential for Mounjaro to temporarily reduce food noise by altering brain wave patterns.
This groundbreaking research, published in November, opens avenues for new therapeutic applications. The identified brain waves are also implicated in chronic pain and potentially other conditions. Further investigation into modifying this effect could lead to treatments without surgical intervention, though experts caution that more research is needed, especially regarding long-term impacts and effects after discontinuing medication.
