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Exercise Boosts Brain Insulin for Dementia Defense
28 Nov
Summary
- Exercise increases brain cells that transport proteins to cells.
- These proteins improve brain cells' ability to respond to insulin.
- Better brain insulin sensitivity may lower risk of dementia.

Recent scientific findings reveal a specific mechanism through which exercise may protect against dementia. A study published in Aging Cell indicated that physical activity boosts the production of neuronal vesicles, specialized brain cells previously underestimated. These vesicles are vital for transporting proteins that enhance the brain's sensitivity to insulin. This improved insulin sensitivity in brain cells is directly linked to better cognitive function, including memory and processing speed, and may offer a proactive defense against neurodegenerative diseases.
Insulin plays a critical role in the brain's neuron function, supporting memory formation and cognitive abilities. As people age, insulin levels in the brain can decrease, potentially leading to brain insulin resistance and impaired cell communication, which are associated with dementia. The research suggests that by improving the body's overall insulin sensitivity, exercise helps counteract this decline, thereby supporting brain health and potentially mitigating dementia risk.
While a precise amount of exercise for dementia prevention is difficult to pinpoint, this study highlights that consistent moderate-to-high intensity workouts over a two-week period demonstrated a positive impact. Experts suggest that exercise, alongside diet and mental stimulation, forms a foundational lifestyle approach for maintaining and improving brain health. This discovery positions exercise as a key tool in the fight against cognitive decline and dementia.



