Home / Health / Estrogen Patch Shortage Leaves Women Scrambling
Estrogen Patch Shortage Leaves Women Scrambling
4 Mar
Summary
- Demand for hormone replacement therapy has surged by 72% since 2021.
- Manufacturers struggle to meet demand, causing widespread pharmacy shortages.
- Doctors suggest alternative estradiol forms like creams and gels.

A significant nationwide surge in demand for hormone replacement therapy (HRT) has resulted in a critical shortage of estrogen patches, impacting women managing perimenopause and menopause symptoms. According to a study by Epic Research, there has been a 72% increase in women using HRT since 2021, a trend that has overwhelmed manufacturers and led to widespread supply disruptions at pharmacies.
Martie Jo Pennisi, a Glendale resident, experienced severe menopause symptoms before finding relief with an estradiol patch and progesterone pill. However, her attempts to refill her prescription were met with unavailability at multiple pharmacies, illustrating the extent of the shortage. Dr. Jessica Shepherd, a menopause expert, noted that while increased demand is positive, it has exposed significant supply chain issues affecting pharmacies universally.
The FDA's removal of a boxed warning on certain hormone therapies, coupled with growing public awareness and open discussion of menopause, has contributed to the rise in prescriptions. For women affected by the shortage, Dr. Shepherd recommends consulting doctors about alternative estradiol forms, including creams, gels, pills, or pellets, emphasizing that efficacy is similar across various delivery methods. Some patients have resorted to more expensive brand-name treatments or adjusted to different patch formulations, underscoring the ongoing challenges in accessing consistent care.