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Summer Heat Threatens Lifesaving EpiPens
30 Jul
Summary
- Extreme heat can degrade EpiPen active ingredients, rendering them ineffective.
- Medicines like EpiPens must be kept cool, away from direct sun and hot cars.
- Certain medications can increase sun sensitivity or cause dehydration in heat.

With temperatures rising significantly across England, a critical warning has been issued regarding the storage of EpiPens and other essential medications. Experts from the MHRA (Medicines and Healthcare products Regulatory Agency) have cautioned that extreme heat can compromise the effectiveness of medicines by breaking down their active ingredients.
This degradation poses a serious risk, particularly for individuals with allergies who depend on EpiPens for emergency treatment of anaphylaxis. Storing these devices in hot cars or direct sunlight can render them useless when urgently required. The MHRA advises keeping all medicines, including tablets, inhalers, and insulin, in a cool, dry place, away from direct sunlight.
Beyond affecting medication efficacy, certain drugs can increase a person's susceptibility to sunburn, dizziness, or dehydration, especially when combined with conditions like asthma, heart disease, or diabetes. Alison Cave, Chief Safety Officer at the MHRA, stressed the importance of recognizing heat-related illness symptoms and staying hydrated.
For those on medication, it is crucial to read patient leaflets for specific storage instructions. During hot weather, individuals should use cool bags when traveling and store medicines in the coolest part of their home. If any medicine changes in color, smell, or texture, it may indicate heat damage, and a pharmacist should be consulted.