Can alkaline phosphatase (ALP) blood test detect osteoporosis?

Yes, a recent study found higher ALP levels in people with osteoporosis, suggesting it could be an early indicator.

What is alkaline phosphatase (ALP) and why is it important for bone health?

ALP is an enzyme that speeds up reactions; elevated levels suggest increased bone turnover, linked to bone loss and fracture risk.

Are there other causes for high alkaline phosphatase besides osteoporosis?

Yes, a high ALP level can also be indicative of liver disease, so further medical evaluation is necessary.

Home / Health / Simple Blood Test May Predict Osteoporosis Risk

Simple Blood Test May Predict Osteoporosis Risk

23 Dec

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Summary

Higher alkaline phosphatase (ALP) levels linked to osteoporosis.
Link strongest in young, healthy women with normal liver enzymes.
Elevated ALP suggests increased bone turnover and fracture risk.

Simple Blood Test May Predict Osteoporosis Risk

New research indicates that a common blood test may offer an early predictor for osteoporosis. A study analyzing data from 2019 to 2024 found that individuals diagnosed with osteoporosis exhibited significantly higher levels of alkaline phosphatase (ALP) in their blood compared to those without the condition.

This correlation was most pronounced among younger women who were metabolically healthy and had normal liver enzyme counts. Elevated ALP levels are suggestive of increased bone turnover, which is closely associated with greater bone loss and an increased likelihood of fractures.

While ALP is a readily available component of standard metabolic panels, experts emphasize it's one piece of the diagnostic puzzle. A high ALP could also indicate other health issues like liver disease, underscoring the need for comprehensive medical evaluation for osteoporosis.

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