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Drinking Just 2-3 Glasses of Wine a Week Increases Deadly Liver Disease Risk
11 Nov
Summary
- Consuming more than 2 drinks/week for women, 3 drinks/week for men increases liver disease risk
- Being overweight/obese is the most important risk factor for metabolic-associated fatty liver disease
- First-line treatment includes diet, exercise, and avoiding alcohol
According to a comprehensive study published in JAMA in November 2025, consuming more than 2 standard alcoholic drinks per week for women and 3 drinks per week for men can dramatically increase the risk of developing a deadly liver disease known as metabolic dysfunction-associated steatotic liver disease (MASLD).
The research, led by a team from the Medical University of Innsbruck, Austria, reviewed over 100 studies on MASLD, previously called non-alcoholic fatty liver disease. The analysis found that being overweight or obese is the single most important risk factor for this potentially life-threatening illness, which is estimated to affect up to 40% of people globally.
