Dental Floss Could Become the Next Vaccine Delivery Tool

Researchers from Texas Tech University and the University of North Carolina have recently discovered that dental floss could eventually be used to deliver vaccines effectively. In animal models, the researchers showed that the thin filament can release vaccines through the tissue between the teeth and gums, triggering the production of antibodies in mucosal surfaces such as the lining of the nose and lungs.

This flossing technique provides an additional line of defense against pathogens like influenza and COVID-19, as the antibodies are stimulated not only in the bloodstream but also on mucosal surfaces. The researchers found that the floss-delivered vaccine produced a superior antibody response compared to the current gold standard of placing the vaccine under the tongue.

The research team aims to further test the effectiveness of this vaccine delivery method in humans using floss picks, which are easier to hold. This approach could be more accessible and less intimidating than traditional needle injections, potentially improving patient compliance. However, the researchers acknowledge that there are still some limitations and questions to be answered, such as the impact of gum disease and the potential for local inflammation.