Clinical Trials: Patients Keen, But Access Lacking

Connecting patients with clinical trials faces numerous obstacles. Despite 71% of chronic condition patients expressing a desire to participate, two-thirds report their healthcare providers have never discussed clinical trials with them. This lack of awareness contributes to up to 86% of trials failing recruitment targets.

Initiatives are underway to address these challenges. In June 2026, the Department of Health and Human Services announced efforts to streamline clinical research, including exploring changes to rules on participant expense reimbursement. The Clinical Trial Modernization Act, urged by nearly 200 advocacy groups in July 2026, aims to allow sponsors to cover medical and non-medical costs for participants.

Participating in trials can offer hope for serious illnesses and contribute to scientific advancement. However, finding suitable trials is difficult, with many patients not knowing how to search, and physicians often lacking the time or resources to identify appropriate options. Geographic proximity and eligibility criteria are also significant hurdles.

Financial burdens, beyond direct trial costs, such as travel, lodging, and childcare, can also prevent participation. While the Affordable Care Act and similar programs cover routine care, incidental expenses remain a barrier. Efforts are focusing on improving access and reducing financial toxicity for participants.