What is MPAL and how rare is it?

MPAL is a rare blood cancer that affects the bone marrow, accounting for less than five percent of all leukaemia cases.

How did John's brother David help him?

David donated his stem cells to John for a life-saving transplant after John's leukaemia relapsed.

What are the results of John's latest transplant?

John's latest results show that 99.5% of the cells in his blood are from his brother David's donation.

Home / Health / Brother's Stem Cells Save Man's Life Twice

Brother's Stem Cells Save Man's Life Twice

19 Apr

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Summary

Man survives rare blood cancer relapse thanks to his brother.
John received a life-saving stem cell transplant from David.
Over 99% of John's blood cells are now from his brother's donation.

Brother's Stem Cells Save Man's Life Twice

John is recovering well after a second stem cell transplant, this time from his younger brother, David. John was diagnosed with MPAL, a rare blood cancer affecting less than five percent of leukaemia cases. He initially received a transplant and returned home in May 2023.

However, in July 2025, John experienced a relapse, feeling unusually breathless after a ten-mile run. Tests confirmed the leukaemia had returned. His brother David, who lives in New York, was previously identified as a potential donor but couldn't donate due to anaemia.

David focused on improving his health, including iron infusions, and was confirmed as a suitable donor. In October 2025, he traveled from the United States to Manchester for the procedure at The Christie. The brothers shared a pizza the night before, strengthening their bond.