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BRCA2 Gene: Double Mastectomy at 21 for Life
27 Nov, 2025
Summary
- Woman underwent double mastectomy at 21 after discovering BRCA2 gene.
- Surgery reduced breast cancer risk from 80% to 4%.
- She now supports others via Instagram's @thebrcajourney.

At 21, Charlotte Hamer made the "no brainer" decision to undergo a double mastectomy after learning she carried the faulty BRCA2 gene, a hereditary risk factor for breast cancer. This proactive surgery, performed in October 2023, reduced her personal risk from 80% to 4%, empowering her to prioritize a long, healthy life.
Her journey was deeply influenced by her mother's earlier battle with and eventual death from breast cancer. While initial reconstructive surgeries presented complications, leading to a temporary flat chest, Charlotte ultimately underwent final reconstructive surgery in November 2024. She views this experience as a profound connection to her mother's struggle.
Now, Charlotte is dedicated to raising awareness about the BRCA2 gene mutation. Alongside a friend, she co-founded @thebrcajourney on Instagram, a global online community providing support and connection for over 45 women navigating similar health challenges.