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Blockbuster Weight Loss Pill Helps Patients Shed Nearly 2 Stone
26 Aug
Summary
- Experimental drug orforglipron helps patients lose over 10% of their weight
- Participants also saw reductions in bad cholesterol, blood fats, and blood pressure
- Pill is easier to produce and transport than injections, likely a cheaper option

According to a recent trial, a new weight loss pill from pharmaceutical giant Lilly is delivering remarkable results. The experimental drug, known as orforglipron, has helped patients shed almost two stone on average, marking a significant breakthrough in the fight against obesity.
The trial involved overweight or obese participants with type 2 diabetes. The highest dose of orforglipron led to a 10.5% weight loss, or 22.9 pounds, over 72 weeks. Patients also experienced reductions in bad cholesterol, blood fats, and blood pressure, further highlighting the drug's potential benefits.
Orforglipron works by targeting the same GLP-1 receptors as popular weight loss injections like Ozempic, Wegovy, and Mounjaro. These medications suppress appetite and make users feel fuller for longer. However, Lilly's pill offers a needle-free alternative that is easier to produce and transport, potentially making it a more cost-effective option.
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Lilly is now preparing to file for regulatory approvals and aims to launch the pill worldwide as early as next year, potentially providing a new and accessible solution for those struggling with obesity and related health issues.