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Bird Flu's Fever-Proof Secret Revealed
28 Nov
Summary
- Bird flu viruses can replicate at temperatures higher than human fevers.
- A specific gene allows avian flu viruses to withstand fever.
- Gene swapping between human and bird flu poses a pandemic threat.

International research led by the University of Cambridge and the University of Glasgow has uncovered how bird flu viruses can overcome fever, a key human defense. These viruses appear to replicate effectively at temperatures exceeding a typical fever, challenging our natural immunity.
The study pinpointed a specific gene, PB1, crucial for viral replication, that grants avian influenza viruses resistance to high temperatures. This finding is particularly concerning because viruses can exchange genes, a phenomenon observed in past pandemics where avian genes transferred to human flu strains.
This gene-swapping capability, especially in hosts like pigs, highlights a continued threat for emerging flu viruses. Researchers emphasize the need for ongoing monitoring of bird flu strains, with tests for fever resistance potentially identifying more virulent strains for better pandemic preparedness.




