Home / Health / Benadryl Danger: Doctors Urge FDA Ban
Benadryl Danger: Doctors Urge FDA Ban
23 Jan
Summary
- Doctors seek to remove Benadryl due to severe risks like brain damage.
- Diphenhydramine impairs driving more than alcohol, leading to accidents.
- Frequent use linked to dementia, heart rhythm issues, and hospitalizations.

Physicians are advocating for the U.S. Food and Drug Administration (FDA) to eliminate over-the-counter diphenhydramine, the active component in Benadryl, from store shelves. Concerns are mounting over potentially severe adverse effects, including significant brain damage.
This first-generation antihistamine easily crosses into the brain, causing profound drowsiness and impairing alertness, which can elevate the risk of accidents. Its impact on driving skills has been noted to be more severe than consuming alcohol above the legal limit.
Beyond sedation, diphenhydramine can cause dry mouth, confusion, and blurred vision, posing particular risks for older adults. Studies published a decade ago and a landmark 2015 JAMA Internal Medicine study indicated that frequent use of such anticholinergic medications is linked to a 54% higher risk of dementia.




