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Body's Own Brewery: The Mystery of Auto-Brewery Syndrome
22 Mar
Summary
- Auto-brewery syndrome causes the body to produce ethanol from food.
- Microbes in the gut ferment carbohydrates, leading to intoxication.
- ABS can cause legal issues, social problems, and mental health concerns.

A rare medical condition known as auto-brewery syndrome (ABS) causes individuals to experience symptoms of drunkenness, such as slurred speech, without consuming alcohol. This phenomenon occurs when bacteria or fungi in the gut excessively produce ethanol, especially after consuming carbohydrate-heavy meals. First identified in the 1950s, ABS remains underdiagnosed and can lead to physical ailments like stomach pain and nausea.
The condition arises from an imbalance in gut microbes, allowing certain species to rapidly ferment carbohydrates. This overgrowth can be exacerbated by factors like antibiotic use or pre-existing conditions such as diabetes and Crohn's disease. Beyond gastrointestinal discomfort, ABS can result in anxiety, depression, and impaired coordination, posing risks for driving and daily activities.
Diagnosing ABS involves physical exams, blood tests, and breathalyzer tests, sometimes including glucose tolerance and stool tests. Treatment focuses on restoring gut microbial balance through dietary changes, potentially including antibiotics or antifungals, and increasing protein intake while reducing carbohydrates. With proper management and lifestyle adjustments, ABS is considered manageable, with a low risk of recurrence.