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Breakthrough Injection Frees Patients from Steroid Pills

Summary

  • New injection allows most severe asthma patients to stop daily steroids.
  • Treatment Tezepelumab targets airway inflammation, reducing side effects.
  • Study shows two-thirds avoided asthma attacks for a full year.
Breakthrough Injection Frees Patients from Steroid Pills

Severe asthma patients may soon ditch daily steroid tablets thanks to a groundbreaking monthly injection. Tezepelumab, a new biologic therapy, effectively targets the root cause of airway inflammation, offering a promising alternative to oral steroids. This innovative treatment was recommended for patients over 12 whose usual medications were insufficient.

The Wayfinder trial, involving nearly 300 individuals across 11 countries, demonstrated remarkable results. A significant 90% of participants successfully reduced their steroid tablet intake, and over half were able to cease daily steroids altogether within a year. This offers relief from the often-debilitating side effects associated with prolonged steroid use.

Beyond reducing steroid dependency, Tezepelumab also showed a dramatic impact on asthma control. Two-thirds of patients remained free from asthma attacks for the entire year-long study period, with improvements noted as early as two weeks. Researchers are optimistic this therapy could transform care for those with the most challenging asthma cases.

Disclaimer: This story has been auto-aggregated and auto-summarised by a computer program. This story has not been edited or created by the Feedzop team.
Tezepelumab is a monthly injection approved for severe asthma patients over 12. It blocks a protein driving airway inflammation, offering an alternative to steroid tablets.
The Wayfinder trial found Tezepelumab enabled 90% of patients to lower steroid doses, with over half stopping daily steroids. Two-thirds also stopped having asthma attacks.
Yes, Tezepelumab is a new biologic therapy that targets inflammation without the side effects of long-term oral steroids, as shown in recent trials.

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