APS: The Silent Clotting Disorder Affecting Women

Antiphospholipid Syndrome (APS) is a significant autoimmune disorder that often presents subtly but can lead to severe health consequences, particularly for women of reproductive age. The condition involves the immune system mistakenly attacking phospholipids, essential fats for blood vessel function, thereby increasing the risk of forming clots in both arteries and veins.

One of the most critical impacts of APS is its strong association with pregnancy complications. It is identified as a leading treatable cause of recurrent miscarriages, especially after the first trimester. Without timely diagnosis and treatment, which typically includes low-dose aspirin and heparin, women may experience repeated pregnancy losses, gestational hypertension, or severe fetal growth restriction.

Misconceptions about clotting disorders often overlook APS, as it can affect young, healthy individuals without traditional risk factors. Symptoms can be diverse, mimicking conditions like lupus, leading to misdiagnosis. Early suspicion and testing for antiphospholipid antibodies are vital to prevent life-threatening events and ensure better outcomes, enabling individuals to lead normal lives with proper management.