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Can Antidepressants Stop Domestic Violence?
2 Dec
Summary
- Sertraline reduced domestic violence reoffending by 30%.
- Trial included comprehensive psychosocial support for participants.
- 96% of partners reported maintained or increased safety.

A world-first trial by the University of New South Wales and University of Newcastle investigated whether the antidepressant sertraline could decrease domestic violence reoffending in impulsive men. The study, involving 630 participants, found that consistent use of sertraline was linked to a 30% reduction in domestic violence reoffending over 24 months.
Beyond medication, the trial incorporated a comprehensive support model. This included trauma-informed counselling, proactive follow-ups, and assistance with navigating social services. This holistic approach proved crucial for participant engagement and improved outcomes.
The intervention demonstrated significant success, with a 44% reduction in repeated domestic violence offending compared to placebo. Furthermore, 96% of partners reported maintained or increased safety, indicating a substantial positive impact on those affected by domestic violence.



